Medications and orthodontics

March 23, 2019

 

 

Medications and teeth movement is a complicated topic in orthodontics. 


In summary:
1. Therapeutic administration of eicosanoids (PGE2 derivatives) resulted in increased tooth movement (Bartzela 2008 systematic review)
2. Nonsteroidal anti-inflammatory drugs (NSAIDs) decreased tooth movement, but non-NSAID analgesics, such as paracetamol (acetaminophen), had no effect. (Bartzela 2008 systematic review)
3. Corticosteroid hormones, parathyroid hormone, and thyroxin have all been shown to increase tooth movement. (Bartzela 2008 systematic review)
4. Estrogens probably reduce tooth movement, although no direct evidence is available. (Bartzela 2008 systematic review)
5. Vitamin D3 stimulates tooth movement, and dietary calcium seemed to reduce it. (Bartzela 2008 systematic review)
6. Bisphosphonates had a strong inhibitory effect. (Bartzela 2008 systematic review)
7. I would like to add that according to my unpublished trial (to be published soon), systemic intake of fluoride reduces teeth movement and OIIRR. (Almuzian 2019, unpublished)
8. I also published a paper which should that systemic intake of CPP-ACP slows down teeth movement and reduces OIIRR (Crowther ..... and Almuzian 2017)

Link to the systematic review
https://lookaside.fbsbx.com/file/PIIS0889540608008858.pdf?token=AWx00F_Q-WhufyyMWvBnwkNyM0nbEBik9ilIkrmVU-EK8gwBhALpw5kDPeMgTWHi6KCqDYzORxcgZ1blZlhQYh83i2p1-uBUyOdLMoLbzh5fFaxZVtgFeZDol7JBvVX2vsT_f7VcHjNwRlY9v_ChfBF40CwdXjr0iHQ9kfpgHQXCxSZ_R3y1MyiqPkWQWhjZnNkFwifldFNmz0n-d6kfsFXi

Link to my CPP-ACP paper
https://academic.oup.com/ejo/article/39/5/541/2953251

#orthodontics #gbbdiploma #orthodonticsmasterygroup #glasgoworthodonticacademy #morth #orthodonticdiploma #dentist #dentistry @g_orthodontic_a 

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